Kinetic energy (also called vis vis, or living force) is energy possessed by a body by virtue of its motion. The kinetic energy of a body is equal to the amount of work needed to establish its velocity and rotation, starting from rest.
Relativity theory states that the kinetic energy of an object grows towards infinity as its velocity approaches the speed of light, and thus that it is impossible to accelerate an object to this boundary.
Where gravity is weak, and objects move at much slower velocities than light (e.g. in everyday phenomena on Earth), Newton's formula is an excellent approximation of relativistic kinetic energy.
Heat is a form of energy due to the total kinetic energy of molecules and atoms of matter. The relationship between heat, temperature and kinetic energy of atoms and molecules is the subject of statistical mechanics. Heat is more akin to work in that it represents a change in internal energy. The energy that heat represents specifically refers to the energy associated with the random translational motion of atoms and molecules in some identifiable matter within a system. The conservation of heat and work form the first law of thermodynamics.