B cellB cells are lymphocytes that play a large role in the primary immune response. The abbreviation "B" stands for the bursa of Fabricius, an organ uniqe to birds where B cells mature; the "B" does not stand for bone marrow, where they are created in all other vertebrates.
There are two types of B cells:
Humoral immunity (the creation of antibodies that circulate in blood plasma and lymph) involves B cell activation.
- Plasma B cells secrete antibodies which effect the destruction of antigens by binding to them and making them easier targets for phagocytes.
- Memory B cells are formed specific to the antigen(s) encountered during the primary immune response; able to live for a long time, these cells can respond quickly upon second exposure to the antigen for which they are specific.
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